CD14 Mouse Monoclonal Antibody [Clone ID: MEM-18]

CAT#: SM3009B

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CD14 mouse monoclonal antibody, clone MEM-18, Biotin

USD 292.00

2 Weeks

    • 100 ug

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Product Data
Clone Name MEM-18
Applications FC, WB
Recommended Dilution Suitable for Indirect Immunofluorescence analysis by Flow Cytometry: 1/1000.
Reactivities Human, Monkey
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen A crude mixture of human urinary proteins precipitated by ammonium sulphate from the urine of a patient suffering from proteinuria
Specificity The antibody MEM-18 reacts with CD14, a 53-55 kDa GPI (glycosylphosphatidylinositol)-linked membrane glycoprotein expressed on monocytes, macrophages and weakly on granulocytes; also expressed by most tissue macrophages. In human, the epitope recognized by MEM-18 is located between amino acids 57-64.
Formulation PBS, pH~7.4
Label: Biotin
State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE)
Preservative: 15 mM Sodium Azide
Label: Conjugated with Biotin-LC-NHS under optimum conditions. The reagent is free of unconjugated biotin.
Concentration lot specific
Conjugation Biotin

Store undiluted at 2-8°C.

Stability Shelf life: one year from despatch.

Gene Name CD14 molecule
Background CD14 is a 55 kDa GPI-anchored glycoprotein, constitutively expressed on the surface of mature monocytes, macrophages, and neutrophils, where serves as a multifunctional lipopolysaccharide receptor; it is also released to the serum both as a secreted and enzymatically cleaved GPI-anchored form. CD14 binds lipopolysaccharide molecule in a reaction catalyzed by lipopolysaccharide-binding protein (LBP), an acute phase serum protein. The soluble sCD14 is able to discriminate slight structural differences between lipopolysaccharides and is important for neutralization of serum allochthonous lipopolysaccharides by reconstituted lipoprotein particles. CD14 affects allergic, inflammatory and infectious processes.
Synonyms CD14
Reference Data
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