Granzyme A (GZMA) Mouse Monoclonal Antibody [Clone ID: GA6]

SKU SM1803P

Granzyme A (GZMA) mouse monoclonal antibody, clone GA6, Purified

Product Data

• Clone Name: GA6
• Application: IHC, WB
• Recommended Dilution: Immunohistochemistry on paraffin sections: 1/50 - 1/200; This product requires antigen retrieval using heat treatment prior to staining of paraffin sections; Sodium citrate buffer pH 6.0 is recommended for this purpose.; Western blotting.
• Reactivity: Human
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Recombinant Granzyme A. Spleen cells from immunised Balb/c mice were fused with cells of the mouse SP2/0 myeloma cell line.
• Specificity: This antibody recognises Granzyme A.
• Buffer: TRIS buffered saline containing 0.09% Sodium Azide; State: Purified; State: Liquid purified IgG
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: granzyme A
• Database Link:
  P12544
• Background: Ganzyma A is a 60kD disulphide-linked homodimeric protein expressed in cytoplasmic granules of cytotoxic lymphocytes. The biological function of Granzyme A is unclear. It would appear that the molecule may have a role in the induction of apoptosis via its activity as a serine protease, but this would seem to be subsidiary to the role of Granzyme B. Granzyme A deficient mice are indistinguishable from normal animals in their response to infection.
• Synonyms: Granzyme-1, Hanukkah factor, H factor, Fragmentin-1, CTLA3, HFSP

Reference Data