CD48 Mouse Monoclonal Antibody [Clone ID: MEM-102]

CAT#: SM1121PS

CD48 mouse monoclonal antibody, clone MEM-102, Purified

Product Images

Surface staining of human peripheral blood with anti-CD48 (MEM-102) PE.

Specifications

Product Data

• Clone Name: MEM-102
• Applications: FC, IHC, IP, WB
• Recommended Dilution: Flow cytometry (2 µg/ml).
  Immunoprecipitation.
  Western blot.
  Immunohistochemistry (paraffin sections).
• Reactivities: Human, Primate
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Raji human Burkitt's lymphoma cell line
• Specificity: The antibody reacts with CD48 antigen (Blast-1), a 40-47 kDa GPI-anchored membrane protein (immunoglobulin supergene family) widely expressed on hematopoietic cells; it is negative on granulocytes, platelets and erythrocytes.
• Formulation: Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
  State: Purified
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Protein-A affinity chromatography; purity: > 95% (by SDS-PAGE)
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C.
  DO NOT FREEZE!
  
• Stability: Shelf life: one year from despatch.
• Gene Name: CD48 molecule
• Database Link:
  Entrez Gene 962 Human
  UniProt ID P09326
• Background: CD48 (Blast-1) belongs to the CD2 subset of the Ig superfamily, which includes CD2, CD2F-10, CD58, CD84, CD150, CD229, CD244 and others. These molecules bind to the same or another members of their family, thus mediate homotypic or heterotypic adhesion. CD48 is a GPI-anchored protein broadly expressed on hematopoietic cells and serves as a high affinity ligand for 2B4 and low affinity ligand for CD2. 2B4-CD48 interaction among NK cells and NK-T cells regulates cell proliferation. Signaling through CD48 results in eosinophil activation and CD48 expression is increased in several infectious diseases.
• Synonyms: BCM1, BLAST1, MEM-102, TCT.1