CD48 Mouse Monoclonal Antibody [Clone ID: MEM-102]
| Product Data | |
| Clone Name | MEM-102 |
|---|---|
| Application | FC, IHC, IP, WB |
| Recommended Dilution | Flow Cytometry. Western Blot. Immunohistochemistry on frozen sections: 1/50 - 1/100 Immunohistochemistry on paraffin sections: This product does not require protein digestion pre-treatment of paraffin sections; This product does not require antigen retrieval using heat treatment prior to staining of paraffin sections. Recommended Positive Control Tissue: Tonsil. |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Specificity | This antibody recognises to the 45kD leucocyte surface glycoprotein specific for the CD48 antigen which is closely related to the activation antigen, Blast-1. It is useful in the detection of CD48 positive cells and may be used in studies to differentiate haemapoietic tumours, sarcomas and melanomas. |
| Buffer | PBS, pH7.4 containing 0.09% Sodium Azide State: Purified State: Liquid purified IgG |
| Concentration | lot specific |
| Purification | Affinity chromatography on Protein G |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch |
| Shipping | Blue Ice |
| Gene Name | CD48 molecule |
| Database Link | |
| Background | CD48 is a glycosyl phophatidyl inositol (GPI) anchored cell surface protein also known as Blast1, HuLy m3, BCM1 (in mouse), and OX45 (in rat). CD48 is strongly expressed on lymphocytes and monocytes and weakly on granulocytes but is absent on platelets, fibrolasts, epithelium and endothelium. CD48 is one of the markers for detecting the defects of GPI anchoring structure on patients with paroxysmal nocturnal hemoglobulinuria (PNH) and serves as a low affinity ligand for CD2. The CD48 antigen is closely related to the activation antigen, Blast 1. |
| Synonyms | BCM1, BLAST1, MEM-102, TCT.1 |
| Reference Data | |
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