Calcitonin (CALCA) Guinea Pig Polyclonal Antibody

CAT#: EUD4701

Calcitonin (CALCA) guinea pig polyclonal antibody, Serum

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: Immunofluorescence.
  Immunohistochemistry on Paraffin and Frozen Sections.
  Working Dilutions: 1/1000-1/1200 for Immunofluorescence microscopy with overnight incubation at 2-8°C.
• Reactivities: Human, Rat
• Host: Guinea Pig
• Clonality: Polyclonal
• Immunogen: Synthetic Human CGRP (Peninsula)
• Specificity: Absorption with 10-100 µg CGRP per ml diluted antiserum abolishes the staining, while while calcitonin does not. Cross-reacts with amylin (IAPP).
• Formulation: State: Serum
  State: Lyophilized Serum
• Reconstitution Method: Dissolve the antiserum in 50-100 μl distilled water, and dilute further in 0.1 M PBS with 1% BSA and 0.09 Sodium Azide.
• Conjugation: Unconjugated
• Storage:

  Prior to reconstitution store at 2-8°C.
  Following reconstitution store undiluted at 2-8°C for one month
  or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: calcitonin related polypeptide alpha
• Database Link:
  Entrez Gene 796 Human
  UniProt ID P06881
• Background: The CGRP-sequence was predicted from the corresponding mRNA. CGRP is present in the C-cells of the thyroid and in nerves, in both brain and periphery, particularly within the sensory system. CGRP is a potent vasodilator, probably involved in neurogenic inflammation. Medullary carcinomas of the thyroid contain large amounts of CGRP.
• Synonyms: Calcitonin gene-related peptide I, Alpha-type CGRP, CALC1, CGRP-I