TAC1 Guinea Pig Polyclonal Antibody

CAT#: EUD4501

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TAC1 guinea pig polyclonal antibody, Serum


Product Datasheet for 'EUD4501'


USD 395.00


Availability*
2 Weeks

Size
    • 50 ul


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Specifications

Product Data
Applications FC, IHC
Recommended Dilution Immunofluorescence: 1/400-1/800 with overnight incubation at 2-8°C.
Immunohistochemistry on Frozen Sections.
Positive Control: Frozen sections of rat colon.
Reactivity Fish, Human, Rabbit, Rat
Host Guinea Pig
Clonality Polyclonal
Immunogen Substance P conjugated to BSA
Specificity This antibody reacts to Substance P.
Absorption with 10-100 µg SP and NKA per ml diluted antiserum abolishes the staining while GRP and NKB do not.
Formulation State: Serum
State: Lyophilized serum
Reconstitution Method Dissolve the antiserum in 50-100 µl distilled water, and dilute further in 0.1 M PBS with 1% BSA and 0.09% NaN3.
Gene Name Homo sapiens tachykinin precursor 1 (TAC1), transcript variant beta
Background Substance P occurs in nerve fibers of the central and peripheral nervous system and in endocrine cells of the gut. It stimulates smooth muscle contraction, gives rise to vasodilation and is involved in sensory functions. Substance P-containing tumors arising in the ileum are often associated with the carcinoid syndrome, characterized by flushing of the skin, diarrhea, bronchoconstriction and sudden drops in blood pressure. Substance P is commonly found in the midgut carcinoids and some of the symptoms may be related to this peptide.
Synonyms Substance-P
Reference Data
Protein Families Druggable Genome, Secreted Protein
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