Lyve1 Rabbit Polyclonal Antibody

CAT#: DP3513P

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Lyve1 rabbit polyclonal antibody, Aff - Purified



USD 326.00

2 Weeks*

Size
    • 50 ug

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Specifications

Product Data
Applications ELISA, FC, IF, IHC, WB
Recommended Dilution ELISA: 1-15 µg/ml.
Western blot: 2-5 µg/ml.
FACS analysis: 3-10 µg/ml. 
Immunofluorescence.
Immunohistochemistry on Paraffin and Frozen Sections: 0.25-4 µg/ml.
Reactivities Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Highly pure (> 95%) recombinant Mouse soluble LYVE-1 (Ala24-Gly228) produced in insect cells (Cat.-No DA3524).
Specificity Cross reactivity of anti-Mouse Lyve-1 with Rat tissue.
The anti-Mouse Lyve-1 polyclonal antibody Cat.-No DP3513P shows a strong cross reaction with Rat Lyve-1 protein.
Formulation PBS, pH 7.4, without preservatives or stabilizers
State: Aff - Purified
State: Lyophilized purified IgG fraction
Reconstitution Method Restore in distilled sterile Water to a concentration of 0.1-1.0 mg/ml.
Purification Antigen Affinity Chromatography
Conjugation Unconjugated
Storage Store lyophilized at 2-8°C for 6 months or at -20°C long term.
After reconstitution store the antibody undiluted at 2-8°C for one month 
or (in aliquots) at -20°C long term.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Background LYVE-1 has been identified as a major receptor for HA (extracellular matrix glycosaminoglycan hyaluronan) on the lymph vessel wall. The deduced amino acid sequence of LYVE-1 predicts a 322-residue type I integral membrane polypeptide 41% similar to the CD44 HA receptor with a 212-residue extracellular domain containing a single Link module the prototypic HA binding domain of the Link protein superfamily. Like CD44, the LYVE-1 molecule binds both soluble and immobilized HA. However, unlike CD44, the LYVE-1 molecule colocalizes with HA on the luminal face of the lymph vessel wall and is completely absent from blood vessels. Hence, LYVE-1 is the first lymph-specific HA receptor to be characterized and is a uniquely powerful marker for lymph vessels themselves.
Synonyms LYVE1, CRSBP-1, CRSBP1, HAR, XLKD1
Reference Data
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.