Myosin-1 / MYH1 Mouse Monoclonal Antibody [Clone ID: MY-32]

SKU DM207

Myosin-1 / MYH1 mouse monoclonal antibody, clone MY-32, Ascites

Product Data

• Clone Name: MY-32
• Application: IHC
• Recommended Dilution: Immunohistochemistry on Paraffin Embedded Sections: Use at 1/25-1/50 in an ABC method (30 minutes at room temperature).; Recommended Positive Control: Skeletal muscle.
• Reactivity: Bovine, Chicken, Guinea Pig, Human, Mouse, Rabbit, Rat
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Rabbit Muscle Myosin.
• Specificity: This antibody recognizes heavy chain of Human skeletal Myosin. It does not stain cardiac or smooth muscle Myosin. ; This antibody stains the fast twitch (type II) isomyosin molecule.; Cellular Localization: Cytoplasmic.
• Buffer: State: Ascites; State: Liquid diluted Ascites; Preservative: Sodium Azide
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Database Link:
  P02562
• Background: Myosin is a 480kDa protein known to interact with actin in muscle and in non-muscle cells. It contains two identical heavy chains (200kDa each) and four light chains (15-26kDa). Myosin molecules consist of two major regions: tails (rod) and heads; they aggregate into filaments through the tail region and interact with actin and with ATP through the head region. Multiple forms of myosin heavy chains exist for each muscle type-skeletal, cardiac, smooth and non-muscle isomyosin forms exist in different types of skeletal muscle, depending on the physiological function of the muscle. These are designated at type I (slow-twitch) and type II (fast-twitch).
• Synonyms: Myosin heavy chain 1, Myosin heavy chain skeletal muscle

Reference Data