Myosin-1 / MYH1 Mouse Monoclonal Antibody [Clone ID: MY-32]

CAT#: DM207-05

Myosin-1 / MYH1 mouse monoclonal antibody, clone MY-32, Ascites

Product Images

Formalin-Fixed, Paraffin-Embedded Human skeletal muscle stained with Myosin, skeletal muscle Antibody Cat.-No DM207 using peroxidase-conjugate and AEC chromogen. Note cytoplasmic staining of muscle cells.

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  Formalin-Fixed, Paraffin-Embedded Human skeletal muscle stained with Myosin, skeletal muscle Antibody Cat.-No DM207 (Clone MY32).

Specifications

Product Data

• Clone Name: MY-32
• Applications: IHC
• Recommended Dilution: Immunohistochemistry on Paraffin Embedded Sections: Use at 1/25-1/50 in an ABC method (30 minutes at room temperature).
  Recommended Positive Control: Skeletal muscle.
• Reactivities: Bovine, Chicken, Guinea Pig, Human, Mouse, Rabbit, Rat
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Rabbit Muscle Myosin.
• Specificity: This antibody recognizes heavy chain of Human skeletal Myosin. It does not stain cardiac or smooth muscle Myosin.
  This antibody stains the fast twitch (type II) isomyosin molecule.
  Cellular Localization: Cytoplasmic.
• Formulation: State: Ascites
  State: Liquid diluted Ascites
  Preservative: Sodium Azide
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C.
• Stability: Shelf life: one year from despatch.
• Database Link:
  UniProt ID P02562
• Background: Myosin is a 480kDa protein known to interact with actin in muscle and in non-muscle cells. It contains two identical heavy chains (200kDa each) and four light chains (15-26kDa). Myosin molecules consist of two major regions: tails (rod) and heads; they aggregate into filaments through the tail region and interact with actin and with ATP through the head region. Multiple forms of myosin heavy chains exist for each muscle type-skeletal, cardiac, smooth and non-muscle isomyosin forms exist in different types of skeletal muscle, depending on the physiological function of the muscle. These are designated at type I (slow-twitch) and type II (fast-twitch).
• Synonyms: Myosin heavy chain 1, Myosin heavy chain skeletal muscle