alpha smooth muscle Actin (ACTA2) Mouse Monoclonal Antibody [Clone ID: 1A4/asm-1]

SKU DM001

alpha smooth muscle Actin (ACTA2) mouse monoclonal antibody, clone 1A4/asm-1, Purified

Product Data

• Clone Name: 1A4/asm-1
• Application: IHC
• Recommended Dilution: Immunohistochemistry on Formalin Fixed Paraffin Embedded Sections: Use Actin antibody at 1/25-1/50 dilution in an ABC method for 30 minutes at room temperature.; Recommended Positive Control: Leiomyoma colon.
• Reactivity: Bovine, Chicken, Human, Mouse, Rabbit, Rat
• Antibody Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: N-terminal decapeptide of alpha-smooth muscle Actin
• Specificity: This antibody is specific to alpha-smooth isoform of actin.; It reacts with smooth muscle cells of vessels and different parenchymes.; The antibody does not cross-react with beta and gamma-cytoplasmic, alpha-sarcomeric and alpha-myocardial actin isoforms.; Cellular Localization: Cytoplasmic.
• Buffer: State: Purified; State: Liquid purified Ig fraction containing Sodium Azide as preservative
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: actin, alpha 2, smooth muscle, aorta
• Database Link:
  P62736
• Background: Smooth muscle actin is expressed in normal smooth muscle and in myoepithelial cells, and also in tumours derived from these cells. Actins are involved in maintaining the structure and integrity of a cell, as well as cell motility. They are highly conserved proteins and make up the majority of the contractile apparatus. To date, six different actin isoforms have been described.
• Synonyms: ACTSA, ACTVS, Alpha-actin-2

Reference Data