MGMT Mouse Monoclonal Antibody [Clone ID: OTI6C4]
CAT#: CF809118
Carrier-free (BSA/glycerol-free) MGMT mouse monoclonal antibody, clone OTI6C4 (formerly 6C4)
Formulation: Standard
Specifications
Product Data | |
Clone Name | OTI6C4 |
Applications | IHC, WB |
Recommended Dilution | WB 1:2000, IHC 1:150 |
Reactivities | Human |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human MGMT (NP_002403) produced in HEK293T cell. |
Formulation | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | O-6-methylguanine-DNA methyltransferase |
Database Link | |
Background | Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. [UniProtKB/Swiss-Prot Function] |
Synonyms | methylguanine-DNA methyltransferase; O-6-methylguanine-DNA methyltransferase; O6-methylguanine-DNA methyltransferase; OTTHUMP00000020741 |
Reference Data | |
Protein Families | Druggable Genome |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Antibody Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
TA809118 | MGMT mouse monoclonal antibody, clone OTI6C4 (formerly 6C4) |
USD 447.00 |
|
TA809118AM | MGMT mouse monoclonal antibody, clone OTI6C4 (formerly 6C4), Biotinylated |
USD 509.00 |
|
TA809118BM | MGMT mouse monoclonal antibody, clone OTI6C4 (formerly 6C4), HRP conjugated |
USD 509.00 |
|
TA809118S | MGMT mouse monoclonal antibody, clone OTI6C4 (formerly 6C4) |
USD 200.00 |
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