ROR1 Mouse Monoclonal Antibody [Clone ID: OTI3D11]

CAT#: CF806826

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Carrier-free (BSA/glycerol-free) ROR1 mouse monoclonal antibody, clone OTI3D11 (formerly 3D11)



  View other "OTI3D11" antibodies (4)

USD 545.00


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Size
    • 100 ug


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Specifications

Product Data
Clone Name OTI3D11
Applications WB
Recommended Dilution WB 1:2000
Reactivities Human, Mouse, Rat
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human ROR1 (NP_005003) produced in HEK293T cell.
Formulation Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 104.1 kDa
Gene Name Homo sapiens receptor tyrosine kinase like orphan receptor 1 (ROR1), transcript variant 1, mRNA.
Background This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun
Synonyms dJ537F10.1; NTRKR1
Reference Data
Protein Families Druggable Genome, Protein Kinase, Transmembrane

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