ARID1A Mouse Monoclonal Antibody [Clone ID: OTI4D1]
CAT#: CF806410
Carrier-free (BSA/glycerol-free) ARID1A mouse monoclonal antibody,clone OTI4D1
Formulation: Standard
Specifications
Product Data | |
Clone Name | OTI4D1 |
Applications | WB |
Recommended Dilution | WB 1:500 |
Reactivities | Human, Mouse, Rat |
Host | Mouse |
Isotype | IgG2a |
Clonality | Monoclonal |
Immunogen | Human recombinant protein fragment corresponding to amino acids 1986-2285 of human ARID1A (NP_006006) produced in E.coli. |
Formulation | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 241.9 kDa |
Gene Name | AT-rich interaction domain 1A |
Database Link | |
Background | This gene encodes a member of the SWI/SNF family, whose members have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. It possesses at least two conserved domains that could be important for its function. First, it has a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus. Second, the C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation. It is thought that the protein encoded by this gene confers specificity to the SNF/SWI complex and may recruit the complex to its targets through either protein-DNA or protein-protein interactions. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
Synonyms | B120; BAF250; BAF250a; BM029; C1orf4; ELD; hELD; hOSA1; MRD14; OSA1; P270; SMARCF1 |
Reference Data | |
Protein Families | Druggable Genome |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Antibody Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
TA806410 | ARID1A mouse monoclonal antibody,clone OTI4D1 |
USD 447.00 |
|
TA806410AM | ARID1A mouse monoclonal antibody,clone OTI4D1, Biotinylated |
USD 509.00 |
|
TA806410BM | ARID1A mouse monoclonal antibody,clone OTI4D1, HRP conjugated |
USD 509.00 |
|
TA806410S | ARID1A mouse monoclonal antibody,clone OTI4D1 |
USD 200.00 |
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