p95 NBS1 (NBN) Mouse Monoclonal Antibody [Clone ID: OTI8E7]

CAT#: CF801410

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Carrier-free (BSA/glycerol-free) NBN mouse monoclonal antibody,clone OTI8E7



USD 600.00


Availability*
In Stock

Size
    • 100 ug


Specifications

Product Data
Clone Name OTI8E7
Applications IHC, WB
Recommended Dilution WB 1:2000, IHC 1:150
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 183-460 of human NBN (NP_002476)produced in E.coli.
Formulation Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 84.8 kDa
Gene Name Homo sapiens nibrin (NBN), transcript variant 1, mRNA.
Background Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. [provided by RefSeq, Jul 2008]
Synonyms AT-V1; AT-V2; ATV; NBS; NBS1; P95
Reference Data
Protein Families Druggable Genome
Protein Pathways Homologous recombination
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