ATRIP Mouse Monoclonal Antibody [Clone ID: OTI5E7]

CAT#: CF504641

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Carrier-free (BSA/glycerol-free) ATRIP mouse monoclonal antibody, clone OTI5E7 (formerly 5E7)



  View other "OTI5E7" antibodies (4)

USD 600.00


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In Stock

Size
    • 100 ug


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Specifications

Product Data
Clone Name OTI5E7
Applications FC, IF, IHC, WB
Recommended Dilution WB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100
Reactivities Human, Dog
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 42-309 of human ATRIP(NP_569055) produced in E.coli.
Formulation Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 85.7 kDa
Gene Name Homo sapiens ATR interacting protein (ATRIP), transcript variant 1, mRNA.
Background The product of this gene is an essential component of the DNA damage checkpoint, and binds to single-stranded DNA coated with replication protein A that accumulates at sites of DNA damage. The encoded protein interacts with the ataxia telangiectasia and Rad3 related protein, a checkpoint kinase, resulting in accumulation of the kinase at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Synonyms DKFZp762J2115; FLJ12343; MGC20625; MGC21482; MGC26740
Reference Data

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