Transferrin Receptor 2 (TFR2) Mouse Monoclonal Antibody [Clone ID: OTI2B4]

SKU CF504563

Carrier-free (BSA/glycerol-free) TFR2 mouse monoclonal antibody, clone OTI2B4 (formerly 2B4)

Product Data

• Clone Name: OTI2B4
• Application: FC, IF, WB
• Recommended Dilution: WB 1:500~2000, IF 1:100, FLOW 1:100
• Reactivity: Human, Monkey, Mouse, Rat
• Antibody Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of human TFR2(NP_003218) produced in HEK293T cell.
• Buffer: Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
• Reconstitution Method: For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Ambient
• Predicted Protein Size: 88.6 kDa
• Gene Name: transferrin receptor 2
• Database Link:
  NP_003218
  Q9UP52
• Background: This gene encodes a single-pass type II membrane protein, which is a member of the transferrin receptor-like family. This protein mediates cellular uptake of transferrin-bound iron, and may be involved in iron metabolism, hepatocyte function and erythrocyte differentiation. Mutations in this gene have been associated with hereditary hemochromatosis type III. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]
• Synonyms: HFE3; TFRC2

Reference Data

• Protein Families: Druggable Genome, Protease, Transmembrane