Proteasome 20S beta 7 (PSMB7) Mouse Monoclonal Antibody [Clone ID: OTI1D1]
CAT#: CF504429
Carrier-free (BSA/glycerol-free) PSMB7 mouse monoclonal antibody, clone OTI1D1 (formerly 1D1)
Formulation: Standard
Specifications
Product Data | |
Clone Name | OTI1D1 |
Applications | IHC, WB |
Recommended Dilution | WB 1:500~2000, IHC 1:150 |
Reactivities | Human, Monkey, Mouse, Rat |
Host | Mouse |
Isotype | IgG2b |
Clonality | Monoclonal |
Immunogen | Human recombinant protein fragment corresponding to amino acids 58-277 of human PSMB7(NP_002790) produced in E.coli. |
Formulation | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 29.8 kDa |
Gene Name | proteasome 20S subunit beta 7 |
Database Link | |
Background | The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. Expression of this catalytic subunit is downregulated by gamma interferon and proteolytic processing is required to generate a mature subunit. This subunit is not present in the immunoproteasome and is replaced by catalytic subunit 2i (proteasome beta 10 subunit). [provided by RefSeq] |
Synonyms | Z |
Reference Data | |
Protein Families | Druggable Genome, Protease |
Protein Pathways | Proteasome |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Antibody Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
TA504429 | PSMB7 (Proteasome 20S beta 7 ) mouse monoclonal antibody, clone OTI1D1 (formerly 1D1) |
USD 447.00 |
|
TA504429AM | PSMB7 (Proteasome 20S beta 7 ) mouse monoclonal antibody, clone OTI1D1 (formerly 1D1), Biotinylated |
USD 509.00 |
|
TA504429BM | PSMB7 (Proteasome 20S beta 7 ) mouse monoclonal antibody, clone OTI1D1 (formerly 1D1), HRP conjugated |
USD 509.00 |
|
TA504429S | PSMB7 (Proteasome 20S beta 7 ) mouse monoclonal antibody, clone OTI1D1 (formerly 1D1) |
USD 200.00 |
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