Catalase (CAT) Mouse Monoclonal Antibody [Clone ID: OTI3C3]

CAT#: CF502497

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Carrier-free (BSA/glycerol-free) CAT mouse monoclonal antibody, clone OTI3C3 (formerly 3C3)



  View other "OTI3C3" antibodies (4)

USD 600.00


Availability*
4 Weeks

Size
    • 100 ug


Specifications

Product Data
Clone Name OTI3C3
Applications FC, IF, IHC, WB
Recommended Dilution WB 1:200~500, IHC 1:150, IF 1:100
Reactivities Human, Mouse, Rat, Dog
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human CAT (NP_111743) produced in HEK293T cell.
Formulation Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 59.6 kDa
Gene Name Homo sapiens catalase (CAT), mRNA.
Background This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene. [provided by RefSeq]
Synonyms MGC138422; MGC138424
Reference Data
Protein Families Druggable Genome
Protein Pathways Amyotrophic lateral sclerosis (ALS), Metabolic pathways, Methane metabolism, Tryptophan metabolism

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.