PDE4A Mouse Monoclonal Antibody [Clone ID: OTI1C8]
CAT#: CF501192
Carrier-free (BSA/glycerol-free) PDE4A mouse monoclonal antibody, clone OTI1C8 (formerly 1C8)
Formulation: Standard
Specifications
Product Data | |
Clone Name | OTI1C8 |
Applications | FC, IF, IHC, WB |
Recommended Dilution | WB 1:2000, IHC 1:50, IF 1:100, FLOW 1:100 |
Reactivities | Human, Rat |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human PDE4A (NP_006193) produced in HEK293T cell. |
Formulation | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 72.0 kDa |
Gene Name | Homo sapiens phosphodiesterase 4A (PDE4A), transcript variant 4, mRNA. |
Database Link | |
Background | Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. Cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. PDE4A is a class IV cAMP-specific PDE |
Synonyms | DPDE2; PDE4; PDE46 |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Progesterone-mediated oocyte maturation, Purine metabolism |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Antibody Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
TA501192 | Anti-PDE4A mouse monoclonal antibody, clone OTI1C8 (formerly 1C8) |
USD 447.00 |
|
TA501192AM | Anti-PDE4A mouse monoclonal antibody, clone OTI1C8 (formerly 1C8), Biotinylated |
USD 509.00 |
|
TA501192BM | Anti-PDE4A mouse monoclonal antibody, clone OTI1C8 (formerly 1C8), HRP conjugated |
USD 509.00 |
|
TA501192S | Anti-PDE4A mouse monoclonal antibody, clone OTI1C8 (formerly 1C8) |
USD 200.00 |
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