BTK Mouse Monoclonal Antibody [Clone ID: OTI3A2]

CAT#: CF501094

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Carrier-free (BSA/glycerol-free) BTK mouse monoclonal antibody, clone OTI3A2 (formerly 3A2)



  View other "OTI3A2" antibodies (4)

USD 600.00


Availability*
In Stock

Size
    • 100 ug


Specifications

Product Data
Clone Name OTI3A2
Applications FC, IF, IHC, WB
Recommended Dilution WB 1:2000, IHC 1:50, IF 1:100, Flow 1:100
Reactivities Human, Mouse, Rat
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human BTK (NP_000052) produced in HEK293T cell.
Formulation Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 76.3 kDa
Gene Name Homo sapiens Bruton tyrosine kinase (BTK), transcript variant 1, mRNA.
Background The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement.
Synonyms AGMX1; AT; ATK; BPK; IMD1; PSCTK1; XLA
Reference Data
Protein Families Druggable Genome, Protein Kinase
Protein Pathways B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Primary immunodeficiency

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