RALBP1 Mouse Monoclonal Antibody [Clone ID: OTI2A6]

CAT#: CF500964

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Carrier-free (BSA/glycerol-free) RALBP1 mouse monoclonal antibody, clone OTI2A6 (formerly 2A6)

Formulation: Standard Carrier-Free



  View other "OTI2A6" antibodies (4)

USD 600.00

4 Weeks*

Size
    • 100 ug

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Specifications

Product Data
Clone Name OTI2A6
Applications IF, IHC, IP, WB
Recommended Dilution WB 1:2000, IHC 1:50, IF 1:100, IP: 4ug/mL
Reactivities Human, Mouse, Rat
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human RALBP1 (NP_006779) produced in HEK293T cell.
Formulation Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 76.0 kDa
Gene Name Homo sapiens ralA binding protein 1 (RALBP1), mRNA.
Background Can activate specifically hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. Mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. Can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. Serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDC2 to switch off endocytosis, One of its substrates would be EPN1/Epsin
Synonyms RIP1; RLIP1; RLIP76
Reference Data
Protein Pathways Pancreatic cancer, Pathways in cancer

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.