Cytochrome P450 Reductase (POR) Mouse Monoclonal Antibody [Clone ID: OTI4G2]

SKU CF500591

Carrier-free (BSA/glycerol-free) POR mouse monoclonal antibody, clone OTI4G2 (formerly 4G2)

Product Data

• Clone Name: OTI4G2
• Application: FC, IHC, WB
• Recommended Dilution: WB 1:500, IHC 1:50, FLOW 1:100
• Reactivity: Human, Mouse, Rat
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of human POR (NP_000932) produced in HEK293T cell.
• Buffer: Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
• Reconstitution Method: For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Ambient
• Predicted Protein Size: 76.9 kDa
• Gene Name: cytochrome p450 oxidoreductase
• Database Link:
  NP_000932
  P16435
• Background: This gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome. [provided by RefSeq]
• Synonyms: CPR; CYPOR; P450R

Reference Data

• Protein Families: Druggable Genome, P450, Transmembrane