STK39 Mouse Monoclonal Antibody [Clone ID: OTI2E10]

SKU CF500497

Carrier-free (BSA/glycerol-free) STK39 mouse monoclonal antibody, clone OTI2E10 (formerly 2E10)

Product Data

• Clone Name: OTI2E10
• Application: IHC, WB
• Recommended Dilution: WB 1:2000 IHC 1:50
• Reactivity: Human, Mouse, Rat
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Full-length protein expressed in 293T cell transfected with human STK39 expression vector
• Buffer: Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
• Reconstitution Method: For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Ambient
• Predicted Protein Size: 59.6 kDa
• Gene Name: serine/threonine kinase 39
• Database Link:
  NP_037365
  Q9UEW8
• Background: This gene encodes a serine/threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress.
• Synonyms: DCHT; PASK; SPAK

Reference Data

• Protein Families: Druggable Genome, Protein Kinase