Neurotrophin 4 (NTF4) Mouse Monoclonal Antibody [Clone ID: OTI2E8]

CAT#: CF500034

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Carrier-free (BSA/glycerol-free) NT4 mouse monoclonal antibody, clone OTI2E8 (formerly 2E8)

Formulation: Standard Carrier-Free



USD 600.00

In Stock*

Size
    • 100 ug

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Specifications

Product Data
Clone Name OTI2E8
Applications IF, IHC, WB
Recommended Dilution WB 1:5000, IHC 1:50, IF 1:50
Reactivities Human, Mouse, Rat
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 81-210 human NT4 (NP_006170) produced in E.coli.
Formulation Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 22.2 kDa
Gene Name Homo sapiens neurotrophin 4 (NTF4), mRNA.
Background NT4 is a member of a family of neurotrophic factors, neurotrophins, that control survival and differentiation of mammalian neurons. The expression of NT4 is ubiquitous and less influenced by environmental signals. While knock-outs of other neurotrophins including nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 prove lethal during early postnatal development, NT4-deficient mice only show minor cellular deficits and develop normally to adulthood.
Synonyms GLC1O; GLC10; NT-4; NT-4/5; NT-5; NT4; NT5; NTF5
Reference Data
Protein Families Druggable Genome, Secreted Protein
Protein Pathways MAPK signaling pathway, Neurotrophin signaling pathway
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