KRT81 Guinea Pig Polyclonal Antibody

CAT#: BP5090

KRT81 guinea pig polyclonal antibody, Serum

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: Immunoblotting: 1/2,000 for Western blotting (ECL method).
  Immunofluorescence Microscopy on Frozen Sections.
  Immunohistochemistry on Frozen Sections.
  Immunohistochemistry on Paraffin Sections: 1/200 for 1h at RT (Trypsin and Microwave pretreatment is required).
• Reactivities: Human, Mouse
• Host: Guinea Pig
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of Human basic hair (trichocytic) keratin K81 (formerly also designated keratin hHb1) coupled to KLH
• Specificity: The antiserum stains specifically Human hair Keratin K81 present in the hair cortex and hair cuticle and tumors derived therefrom.
• Formulation: State: Serum
  State: Liquid Stabilized Antiserum
  Preservative: 0.09% Sodium Azide, 0.5% BSA
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C.
  DO NOT FREEZE!
  
• Stability: Shelf life: one year from despatch.
• Gene Name: keratin 81
• Database Link:
  Entrez Gene 3887 Human
  UniProt ID Q14533
• Background: KRT81 (Keratin 81) is a type II hair keratin. It is a basic protein which heterodimerizes with type I keratins to form hair and nails. It is found primarily in the hair cortex. Mutations in KRT81 have been observed in patients with, monilethrix, a rare dominant hair disease characterized by beaded or moniliform hair that results from the periodic thinning of the hair shaft and shows a high propensity to excess weathering and fracturing.
• Synonyms: KRT81, KRTHB1, MLN137, Keratin hair basic 1, ghHKb1, ghHb1, Keratin-81, K81, K2.9, MLN 137