Cytokeratin 8 (KRT8) Guinea Pig Polyclonal Antibody

SKU
BP5075
Cytokeratin 8 (KRT8) guinea pig polyclonal antibody, Serum
$545.00
2 Weeks*
Specifications
Product Data
Application IF, IHC, WB
Recommended Dilution Immunoblotting: 1/3000 (ECL method). 
Immunohistochemistry on Frozen Sections: 1/50 - 1/250.
Immunohistochemistry on Paraffin Sections: 1/50 - 1/250 (after microwave treatment or trypsin). 
Immunohistochemistry on Cytological Material. 
Incubation Time:
1 h at RT, extended with paraffin sections. 
Positive Control: Human intestinal epithelia.
Reactivity Bovine, Human, Mouse, Rat
Antibody Host Guinea Pig
Clonality Polyclonal
Immunogen Synthetic peptide (C-MSIRVTQKSYKVST) of Human keratin K8 (formerly also designated cytokeratin 8), coupled to KLH.
Specificity Specific for Keratin K8. Marker for discrimination of simple / non-stratified epithelia from those of stratified origin.
Basic Human keratin K8 (Mr 52 000) of all simple type and complex epithelia.
Buffer State: Serum
State: Liquid Stabilized Serum
Stabilizer: 0.5% BSA
Preservative: 0.09% Sodium Azide
Conjugation Unconjugated
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Gene Name keratin 8
Database Link
Background Cytokeratin 8 belongs to the type B (basic) subfamily of high molecular weight keratins and exists in combination with cytokeratin 18. Cytokeratin 8 is primarily found in the non squamous epithelia and is present in majority of adenocarcinomas and ductal carcinomas. It is absent in squamous cell carcinomas. Hepatocellular carcinomas are defined by the use of antibodies that recognize only cytokeratin polypeptides 8 and 18.
Synonyms KRT8, CYK8, Cytokeratin-8, CK8, Keratin-8, K8, Cytokeratin endo A
Reference Data
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.