Neurofilament(NEFM) Mouse Monoclonal Antibody [Clone ID: NF403]

CAT#: BM5505

Mouse monoclonal anti-Neurofilament M (160 kD) antibody, cloneNF403, Supernatant


 Product Datasheet for 'BM5505'

USD 360.00


Availability*
2 Weeks

Size
    • 1 ml


Product images

Specifications

Product Data
Clone Name NF403
Recommend Dilution IHC, WB
Reactivity Bovine, Guinea Pig, Human, Rat
Host Mouse
Clonality Monoclonal
Immunogen Neurofilament preparation isolated from calf brain tissue.
Isotype IgG1
Purification Liquid Culture Supernatant containing 0.09% Sodium Azide as preservative. Supernatant
Predicted Protein Size ~102.3kDa
Gene Name neurofilament, medium polypeptide
Background Neurofilaments can be defined as the intermediate or 10nm diameter filaments found in neuronal cells. They are composed a mixture of subunits which often includes the neurofilament triplet proteins, NF-L, NF-M and NF-H. Neurofilaments may also include peripherin, alpha-internexin, nestin and in some cases vimentin. Antibodies to the various neurofilament subunits are very useful cell type markers since the proteins are quite abundant, biochemically stable. This antibody was raised against the C-terminal region of NF-M, a region highly conserved between NF-M molecules in different species. Accordingly the antibody recognizes all mammalian and avian NF-M molecules. The name NF-M refers to the fact that this is the "middle" or "medium" protein of neurofilament triplet, the other two proteins being "low" or "light" (NF-L) and "high" or "heavy" (NF-H). NF-M is sometimes also referred to as NEF3 or Neurofilament
Synonyms NEF3|NF-M|NFM
Reference Data
Protein Pathways Amyotrophic lateral sclerosis (ALS)
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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