LRPAP1 Mouse Monoclonal Antibody [Clone ID: 7F1]

CAT#: BM5054

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LRPAP1 mouse monoclonal antibody, clone 7F1, Purified



USD 340.00


Availability*
2 Weeks

Size
    • 50 ug


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Specifications

Product Data
Clone Name 7F1
Applications IF, IHC, WB
Recommended Dilution Immunoblotting.
Immunofluorescence.
Immunohistochemistry: 1/20.
Ligand-binding assays.
Reactivity Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Human RAP.
Specificity This antibody BM5054 (7F1) reacts with the 39 kDa RAP protein, which is cosynthesized with Human LRP/alpha2MR (low density lipoprotein receptor-related protein/alpha2-Macro-Globulin Receptor).
It inhibits the binding of ligands, e.g. tPA, uPA, VLDL, liproprotein lipase, and alpha2-Macroglobulin-proteinase complexes to LRP/A2MR.
Formulation PBS buffer, pH 7.4 containing 0.5% BSA as stabilizer.
State: Purified
State: Lyophilized purified IgG fraction.
Reconstitution Method Restore in 1 ml distilled water.
Purification Affinity Chromatography on Protein A .
Storage Prior to reconstitution store at 2-8°C.
Following reconstitution store the antibody at -20°C.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Background Low density lipoprotein receptor-related protein-associated protein 1 (RAP) interacts with LRP1/alpha-2-macroglobulin receptor and glycoprotein 330. It is present on the cell surface forming a complex with the alpha 2 macroglobulin receptor heavy and light chains. Binds LRP1B; binding is followed by internalization and degradation. In complex with the alpha 2 MR or gp330, it may have some role in the pathogenesis of membrane glomerular nephritis.
Synonyms Alpha-2-MRAP, RAP
Reference Data
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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