LRPAP1 Mouse Monoclonal Antibody [Clone ID: 7F1]

SKU BM5054

LRPAP1 mouse monoclonal antibody, clone 7F1, Purified

Product Data

• Clone Name: 7F1
• Application: IF, IHC, WB
• Recommended Dilution: Immunoblotting.; Immunofluorescence.; Immunohistochemistry: 1/20.; Ligand-binding assays.
• Reactivity: Human
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Human RAP.
• Specificity: This antibody BM5054 (7F1) reacts with the 39 kDa RAP protein, which is cosynthesized with Human LRP/alpha2MR (low density lipoprotein receptor-related protein/alpha2-Macro-Globulin Receptor).; It inhibits the binding of ligands, e.g. tPA, uPA, VLDL, liproprotein lipase, and alpha2-Macroglobulin-proteinase complexes to LRP/A2MR.
• Buffer: PBS buffer, pH 7.4 containing 0.5% BSA as stabilizer.; State: Purified; State: Lyophilized purified IgG fraction.
• Reconstitution Method: Restore in 1 ml distilled water.
• Purification: Affinity Chromatography on Protein A .
• Conjugation: Unconjugated
• Storage: Prior to reconstitution store at 2-8°C.; Following reconstitution store the antibody at -20°C.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Ambient
• Gene Name: LDL receptor related protein associated protein 1
• Database Link:
  P30533
• Background: Low density lipoprotein receptor-related protein-associated protein 1 (RAP) interacts with LRP1/alpha-2-macroglobulin receptor and glycoprotein 330. It is present on the cell surface forming a complex with the alpha 2 macroglobulin receptor heavy and light chains. Binds LRP1B; binding is followed by internalization and degradation. In complex with the alpha 2 MR or gp330, it may have some role in the pathogenesis of membrane glomerular nephritis.
• Synonyms: Alpha-2-MRAP, RAP

Reference Data