Phospholipase D2 (PLD2) pTyr169 Rabbit Polyclonal Antibody
| Product Data | |
| Application | IHC, WB |
|---|---|
| Recommended Dilution | Western blot: 1:500~1:1000. Immunohistochemistry on paraffin sections: 1:50~1:100. |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Peptide sequence around phosphorylation site of tyrosine 169(E-N-Y(p)-L-N) derived from Human PLD2 (KLH-conjugated) |
| Specificity | The antibody detects endogenous levels of PLD2 only when phosphorylated at tyrosine 169. |
| Buffer | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol State: Aff - Purified State: Liquid Ig fraction |
| Concentration | lot specific |
| Purification | Affinity chromatography using epitope-specific peptide |
| Conjugation | Unconjugated |
| Storage | Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Predicted Protein Size | 95 kDa |
| Gene Name | phospholipase D2 |
| Database Link | |
| Background | Phosphatidylcholine (PC)-specific phospholipases D (PLDs) catalyze the hydrolysis of PC to produce phosphatidic acid and choline. Activation of PC-specific PLDs occurs as a consequence of agonist stimulation of both tyrosine kinase and G protein-coupled receptors. PC-specific PLDs have been proposed to function in regulated secretion, cytoskeletal reorganization, transcriptional regulation, and cell cycle control. |
| Synonyms | Phospholipase D2, PLD 2, Choline phosphatase 2, PLD1C, Phosphatidylcholine-hydrolyzing phospholipase D2 |
| Reference Data | |
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