VPS39 pSer39 Rabbit Polyclonal Antibody
Product Data | |
Application | ELISA, IHC, WB |
---|---|
Recommended Dilution | ELISA. |
Reactivity | Human |
Antibody Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Synthetic peptide derived from an internal domain of Human Vam6 protein |
Specificity | Reacts with Human VPS39 102 kDa protein. Cross reacts with Mouse and other species. |
Buffer | State: Serum State: Lyophilized powder Preservative: None |
Reconstitution Method | Restore in distilled water. |
Conjugation | Unconjugated |
Storage | Prior to reconstitution store the antibody at -20°C. |
Stability | Shelf life: one year from despatch. |
Shipping | Ambient |
Gene Name | VPS39, HOPS complex subunit |
Database Link | |
Background | VPS39 is the mammalian homolog of the yeast vacuolar protein VAM6, that in mammals, promotes lysosome clustering and fusion in vivo. VPS39 is also thought to modulate the TGF-b response by coupling the TGF-b receptor complex to the Smad pathway. Similar to the related protein TRAP1, the VPS39 protein is essential for early embryonic development, with mice lacking VPS39 dying at or before E6.5. |
Synonyms | KIAA0770, VAM6, Vam6/Vps39-like protein |
Reference Data |
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