PLCZ1 Rabbit Polyclonal Antibody

CAT#: AP55157SU-N

PLCZ1 rabbit polyclonal antibody, Serum

Specifications

Product Data

• Applications: ELISA, IF, WB
• Recommended Dilution: Western Blot. 1/100-1/1000.
  ELISA.
  Immunocytochemistry 1/50-1/1000.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptides derived frominternal parts of PLC-zeta-1
• Specificity: This antibody reacts with human PLC zeta protein. No cross reaction.
• Formulation: 0.1M Tris, 0.1M Glycine, 2% Sucrose
  State: Serum
  State: Lyophilized Powder
• Reconstitution Method: Restore in distilled water.
• Concentration: lot specific
• Purification: Antiserum
• Conjugation: Unconjugated
• Storage:

  Prior to reconstitution store at -20°C.
  Following reconstitution store undiluted at 2-8°C for one month
  or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Database Link:
  Entrez Gene 89869 Human
  UniProt ID Q86YW0
• Background: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. In vitro, hydrolyzes PtdIns(4,5)P2 in a Ca2+-dependent manner. Triggers intracellular Ca2+ oscillations in oocytes solely during M phase and is involved in inducing oocyte activation and initiating embryonic development up to the blastocyst stage. Is therefore a strong candidate for the egg-activating soluble sperm factor that is transferred from the sperm into the egg cytoplasm following gamete membrane fusion.
• Synonyms: Phospholipase C-zeta-1, Phospholipase C zeta 1, PLC-zeta-1