ZRANB1 (C-term) Rabbit Polyclonal Antibody

CAT#: AP54739PU-N

ZRANB1 (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of ZRANB1 Antibody (C-term) in K562 cell line lysates (35 ug/lane). ZRANB1 (arrow) was detected using the purified Pab.

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  Western blot analysis of ZRANB1 Antibody (C-term) in mouse cerebellum tissue lysates (35 ug/lane). ZRANB1 (arrow) was detected using the purified Pab.

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  ZRANB1 Antibody (C-term) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ZRANB1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Peptide ELISA: 1/1000.
  Western blot: 1/100~1/500.
  Immunohistochemistry: 1/50~1/100.
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 665~692 amino acids from the C-terminal region of human ZRANB1
• Specificity: This antibody detects ZRANB1 (C-term).
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Aff - Purified
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Protein A column followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: zinc finger RANBP2-type containing 1
• Database Link:
  Entrez Gene 360216 MouseEntrez Gene 54764 Human
  UniProt ID Q9UGI0
• Background: ZRANB1 is a positive regulator of the Wnt signaling pathway that specifically cleaves 'Lys-63'-linked ubiquitin chains. It acts by deubiquitinating APC protein, a negative regulator of Wnt-mediated transcription and may also modulate TNF-alpha signaling.
• Synonyms: TRABID
• Note: Molecular Weight: 80967 Da

Reference Data

• Protein Families: Druggable Genome