ZCRB1 (C-term) Rabbit Polyclonal Antibody

CAT#: AP54628PU-N

ZCRB1 (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

ZCRB1 Antibody (C-term) western blot analysis in mouse Neuro-2a cell line lysates (35 ug/lane). This demonstrates the ZCRB1 antibody detected the ZCRB1 protein (arrow).

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  ZCRB1 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ZCRB1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Immunohistochemistry on paraffin sections: 1:10~50.
  ELISA: 1:1;000.
  Western blot: 1:100~500.
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 183-212 amino acids from the C-terminal region of human ZCRB1
• Specificity: This antibody detects ZCRB1 (C-term).
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Aff - Purified
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Protein A column followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens zinc finger CCHC-type and RNA binding motif containing 1 (ZCRB1)
• Database Link:
  Entrez Gene 67197 MouseEntrez Gene 85437 Human
  UniProt ID Q8TBF4
• Background: Pre-mRNA splicing is catalyzed by the spliceosome. U12-type spliceosome binds U12-type pre-mRNAs and recognizes the 5' splice site and branch-point sequence. U11 and U12 snRNPs are components of U12-type spliceosome and function as a molecular bridge connecting both ends of the intron. The protein encoded by this gene contains a RNA recognition motif. It was identified as one of the protein components of U11/U12 snRNPs. This protein and many other U11/U12 snRNP proteins are highly conserved in organisms known to contain U12-type introns. These proteins have been shown to be essential for cell viability, suggesting the key roles in U12-type splicing.
• Synonyms: MADP-1; MADP1; MGC26805; RBM36; U11/U12-31K; ZCCHC19
• Note: Molecular Weight: 24592 Da