Uroplakin Ib (UPK1B) (Center) Rabbit Polyclonal Antibody

SKU AP54476PU-N

Uroplakin Ib (UPK1B) (Center) rabbit polyclonal antibody, Aff - Purified

Product Data

• Application: FC, IHC, WB
• Recommended Dilution: Western blot: 1:1,000.; Immunohistochemistry on paraffin sections: 1:50~100.; Flow cytometry: 1:10~50.
• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 159~188 amino acids from the Central region of human UPK1B
• Specificity: This antibody detects Uroplakin-1b (UPK1B) (Center).
• Buffer: PBS with 0.09% (W/V) sodium azide; State: Aff - Purified; State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Protein A column followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: uroplakin 1B
• Database Link:
  O75841
• Background: UPK1B is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This protein is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions.
• Synonyms: UP1b, Uroplakin Ib, UPIb, Tetraspanin-20, TSPAN20, Tspan-20
• Note: Molecular Weight: 29643 Da

Reference Data

• Protein Families: Transmembrane