UNC5D (Center) Rabbit Polyclonal Antibody

CAT#: AP54461PU-N

UNC5D (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

UNC5D Antibody (Center) western blot analysis in 293 cell line lysates (35 ug/lane). This demonstrates the UNC5D antibody detected the UNC5D protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1:1;000.
  Western blot: 1:100~500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 482-511 amino acids from the Central region of human UNC5D
• Specificity: This antibody detects UNC5D (Center).
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Aff - Purified
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Protein A column; followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: unc-5 netrin receptor D
• Database Link:
  Entrez Gene 137970 Human
  UniProt ID Q6UXZ4
• Background: UNC5D is receptor for netrin. May be involved in axon guidance by mediating axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand (By similarity).
• Synonyms: Protein unc-5 homolog D, Unc-5 homolog 4, KIAA1777, UNC5H4, UNQ6012/PRO34692
• Note: Molecular Weight: 105880 Da

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Axon guidance