UGT8 (Center) Rabbit Polyclonal Antibody
Product Data | |
Application | IHC, WB |
---|---|
Recommended Dilution | ELISA: 1:1;000. Western blot: 1:100~500. Immunohistochemistry on paraffin sections: 1:10~50. |
Reactivity | Human, Mouse |
Antibody Host | Rabbit |
Isotype | Ig |
Clonality | Polyclonal |
Immunogen | KLH conjugated synthetic peptide between 373-401 amino acids from the Central region of human UGT8 |
Specificity | This antibody detects UGT8 / UGT4 (Center). |
Buffer | PBS with 0.09% (W/V) sodium azide State: Aff - Purified State: Liquid Ig fraction |
Concentration | lot specific |
Purification | Protein A column followed by peptide affinity purification |
Conjugation | Unconjugated |
Storage | Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Shipping | Blue Ice |
Gene Name | UDP glycosyltransferase 8 |
Database Link | |
Background | Galactocerebrosides are abundant sphingolipids of the myelin membrane of the central nervous system and peripheral nervous system and are also present in small amounts in kidney. The key enzymatic step in the biosynthesis of galactocerebrosides consists of the transfer of galactose to ceramide catalyzed by UDP-galactose ceramide galactosyltransferase (CGT, EC 2.4.1.45). The enzyme encoded by the CGT gene is the first involved in complex lipid biosynthesis in the myelinating oligodendrocyte. [supplied by OMIM]. |
Synonyms | UDP-galactose-ceramide galactosyltransferase, Ceramide UDP-galactosyltransferase, Cerebroside synthase, CGT |
Note | Molecular Weight: 61438 Da |
Reference Data | |
Protein Families | Transmembrane |
Protein Pathways | Metabolic pathways, Sphingolipid metabolism |
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