TRADD (Center) Rabbit Polyclonal Antibody

SKU AP54350PU-N

TRADD (Center) rabbit polyclonal antibody, Aff - Purified

Product Data

• Application: FC, IF, IHC, WB
• Recommended Dilution: ELISA: 1:1;000.; Western blot: 1:100~500.; Immunohistochemistry on paraffin sections: 1:50~100.; Flow cytometry: 1:10~50.; Immunofluorescence: 1:10~50.
• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 133-159 amino acids from the Central region of human TRADD
• Specificity: This antibody detects TRADD (Center).
• Buffer: PBS with 0.09% (W/V) sodium azide; State: Aff - Purified; State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Protein A column followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: TNFRSF1A associated via death domain
• Database Link:
  Q15628
• Background: The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. [provided by RefSeq].
• Synonyms: MGC11078
• Note: Molecular Weight: 34247 Da

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Adipocytokine signaling pathway, Apoptosis, RIG-I-like receptor signaling pathway