ST6GALNAC1 (N-term) Rabbit Polyclonal Antibody

CAT#: AP54057PU-N

ST6GALNAC1 (N-term) rabbit polyclonal antibody, Aff - Purified

Product Images

ST6GALNAC1 Antibody (N-term) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the ST6GALNAC1 antibody detected the ST6GALNAC1 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100 - 1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 35-65 amino acids from the N-terminal region of human ST6GALNAC1
• Specificity: This antibody reacts to ST6GALNAC1.
• Formulation: PBS
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.09% (W/V) sodium azide
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Conjugation: Unconjugated
• Storage:

  Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Predicted Protein Size: 68564 Da
• Gene Name: ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1
• Database Link:
  Entrez Gene 55808 Human
  UniProt ID Q9NSC7
• Background: Glycosylation of proteins affects cell-cell interaction, interactions with the matrix, and the functions of intracellular molecules. ST6GALNAC1 transfers a sialic acid, N-acetylneuraminic acid (NeuAc), in an alpha-2,6 linkage to O-linked GalNAc residues. The cancer-associated sialyl-Tn (sTn) antigen is formed by ST6GALNAC1-catalyzed sialylation of GalNAc residues on mucins (Ikehara et al., 1999 [PubMed 10536037]; Sewell et al., 2006 [PubMed 16319059]).
• Synonyms: ST6GalNAc I, ST6GalNAcI, Sialyltransferase 7A, SIAT7A, SIAT7-A, HSY11339

Reference Data

• Protein Families: Transmembrane
• Protein Pathways: Metabolic pathways, O-Glycan biosynthesis