FISH (SH3PXD2A) (N-term) Rabbit Polyclonal Antibody
| Product Data | |
| Application | WB |
|---|---|
| Recommended Dilution | ELISA: 1/1,000. Western blotting: 1/100-1/500. |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Isotype | Ig |
| Clonality | Polyclonal |
| Immunogen | KLH conjugated synthetic peptide between 221-250 amino acids from the N-terminal region of Human SH3PXD2A |
| Specificity | Recognizes SH3PXD2A (N-term) . |
| Buffer | PBS State: Aff - Purified State: Liquid purified Ig fraction Preservative: 0.09% (W/V) Sodium Azide |
| Concentration | lot specific |
| Purification | Protein A column followed by peptide Affinity purification |
| Conjugation | Unconjugated |
| Shipping | Blue Ice |
| Gene Name | SH3 and PX domains 2A |
| Database Link | |
| Background | SH3PXD2A is required for podosome formation, degradation of the extracellular matrix, and for the invasiveness of some cancer cells. Binds phosphatidylinositol 3-phosphate (PtdIns(3)P) and phosphatidylinositol 3,4-biphosphate (PtdIns(3,4)P2). In association with ADAM12, mediates the neurotoxic effect of beta-amyloid peptide. |
| Synonyms | FISH, KIAA0418, SH3MD1, TKS5 |
| Note | Molecular Weight: 125289 Da |
| Reference Data | |
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