Neuroserpin (SERPINI1) (N-term) Rabbit Polyclonal Antibody

SKU AP53865PU-N

Neuroserpin (SERPINI1) (N-term) rabbit polyclonal antibody, Aff - Purified

Product Data

• Application: IF, IHC, WB
• Recommended Dilution: ELISA: 1/1,000.; Western blotting: 1/100-1/500.; Immunofluorescence: 1/10-1/50.; Immunohistochemistry: 1/50-1/100.
• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 26-53 amino acids from the N-terminal region of Human SERPINI1.
• Specificity: Recognizes SERPINI1 (N-term).
• Buffer: PBS with 0.09% (W/V) Sodium Azide as preservative; State: Aff - Purified; State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column followed by peptide Affinity purification
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: serpin family I member 1
• Database Link:
  Q99574
• Background: This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The protein is primarily secreted by axons in the brain, and preferentially reacts with and inhibits tissue-type plasminogen activator. It is thought to play a role in the regulation of axonal growth and the development of synaptic plasticity. Mutations in this gene result in familial encephalopathy with neuroserpin inclusion bodies (FENIB), which is a dominantly inherited form of familial encephalopathy and epilepsy characterized by the accumulation of mutant neuroserpin polymers. Multiple alternatively spliced variants, encoding the same protein, have been identified.
• Synonyms: Serpin I1, PI12, PI-12
• Note: Molecular Weight: 46427 Da

Reference Data

• Protein Families: Druggable Genome, Secreted Protein