CD162 (SELPLG) (C-term) Rabbit Polyclonal Antibody

CAT#: AP53840PU-N

CD162 (SELPLG) (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of SELPLG Antibody (C-term) in Jurkat cell line lysates (35ug/lane). This demonstrates the SELPLG antibody detected the SELPLG protein (arrow).

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  flow cytometric analysis of Jurkat cells using SELPLG Antibody (C-term) (Right histogram) compared to a negative control cell (Left histogram). FITC-conjugated Goat-anti-Rabbit secondary antibodies were used for the analysis.

Specifications

Product Data

• Applications: FC, WB
• Recommended Dilution: ELISA: 1/1,000.
  Western blotting: 1/100-1/500.
  Flow Cytometry: 1/10-1/50.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 386-413 amino acids from the C-terminal region of Human SELPLG
• Specificity: Recognizes SELPLG (C-term).
• Formulation: PBS with 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column followed by peptide Affinity purification
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: selectin P ligand
• Database Link:
  Entrez Gene 6404 Human
  UniProt ID Q14242
• Background: SELPLG is the high affinity counter-receptor for P-selectin on myeloid cells and stimulated T lymphocytes. As such, it plays a critical role in the tethering of these cells to activated platelets or endothelia expressing P-selectin. The organization of the SELPG gene closely resembles that of CD43 and the human platelet glycoprotein GpIb-alpha both of which have an intron in the 5-prime-noncoding region, a long second exon containing the complete coding region, and TATA-less promoters.
• Synonyms: PSGL-1, Selectin P ligand, SELPLG
• Note: Molecular Weight: 43201 Da

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs)