SEC61B (Center) Rabbit Polyclonal Antibody
| Product Data | |
| Application | WB |
|---|---|
| Recommended Dilution | ELISA: 1/1,000. Western blotting: 1/100-1/500. |
| Reactivity | Human, Mouse |
| Antibody Host | Rabbit |
| Isotype | Ig |
| Clonality | Polyclonal |
| Immunogen | KLH conjugated synthetic peptide between 41-70 amino acids from the Central region of Human SEC61B (NP_006799.1) |
| Specificity | Recognizes SEC61B (Center). |
| Buffer | PBS with 0.09% (W/V) Sodium Azide as preservative State: Aff - Purified State: Liquid purified Ig fraction |
| Concentration | lot specific |
| Purification | Protein A column followed by peptide Affinity purification |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | Sec61 translocon beta subunit |
| Database Link | |
| Background | The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma. This gene encodes the beta-subunit protein. The Sec61 subunits are also observed in the post-ER compartment, suggesting that these proteins can escape the ER and recycle back. There is evidence for multiple polyadenylated sites for this transcript. |
| Synonyms | SEC61B |
| Note | Molecular Weight: 9974 Da |
| Reference Data | |
| Protein Families | Transmembrane |
| Protein Pathways | Vibrio cholerae infection |
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