RAD54 (RAD54L) (C-term) Rabbit Polyclonal Antibody
RAD54 (RAD54L) (C-term) rabbit polyclonal antibody, Aff - Purified
|Applications||FC, IHC, WB|
|Recommended Dilution||ELISA: 1/1000.
Western Blot: 1/100-1/500.
Flow Cytometry: 1/10-1/50.
|Immunogen||KLH conjugated synthetic peptide between 641-671 amino acids from the C-terminal region of Human RAD54|
|Specificity||This antibody recognizes Human RAD54L (C-term).|
State: Aff - Purified
State: Liquid purified Ig fraction
Preservative: 0.09% Sodium Azide
|Purification||Affinity Chromatography on Protein A|
Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
|Stability||Shelf life: one year from despatch.|
|Gene Name||Homo sapiens RAD54-like (S. cerevisiae) (RAD54L), transcript variant 2|
|Background||The protein encoded by this gene belongs to the DEAD-like helicase superfamily, and shares similarity with Saccharomyces cerevisiae Rad54, a protein known to be involved in the homologous recombination and repair of DNA. This protein has been shown to play a role in homologous recombination related repair of DNA double-strand breaks. The binding of this protein to double-strand DNA induces a DNA topological change, which is thought to facilitate homologous DNA paring, and stimulate DNA recombination. Alternative splicing results in multiple transcript variants encoding the same protein.|
|Synonyms||RAD54A, RAD54 homolog, hRAD54, hHR54|
|Note||Molecular Weight: 84352 Da|
|Protein Families||Druggable Genome, Stem cell - Pluripotency|
|Protein Pathways||Homologous recombination|