PTP gamma (PTPRG) (Center) Rabbit Polyclonal Antibody

CAT#: AP53515PU-N

PTP gamma (PTPRG) (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis in mouse lung tissue lysates (35ug/lane) using PTPRG / PTPG antibody. This demonstrates the PTPRG antibody detected the PTPRG protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution:

  Western blot: 1/100-1/500.
  Enzyme immunoassay: 1/1000.

• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: Synthetic peptide - KLH conjugated - corresponding to the central region (between 670-700aa) of human PTPRG / PTPG
• Specificity: This antibody recognizes PTPRG / PTPG.
• Formulation: PBS with 0.09% (W/V) Sodium azide
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Purified through a Protein A column followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: protein tyrosine phosphatase, receptor type G
• Database Link:
  Entrez Gene 5793 Human
  UniProt ID P23470
• Background: The protein encoded by the PTPRG gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this PTP contains a carbonic anhydrase-like (CAH) domain, which is also found in the extracellular region of PTPRBETA/ZETA. This gene is located in a chromosomal region that is frequently deleted in renal cell carcinoma and lung carcinoma, thus is thought to be a candidate tumor suppressor gene.
• Synonyms: HPTPG; H_RG317H01.1; PTPG; R-PTP-GAMMA; RPTPG
• Note: Molecular Weight: 162003 Da

Reference Data

• Protein Families: Druggable Genome, Phosphatase