LOC105369264 (Center) Rabbit Polyclonal Antibody

SKU AP53510PU-N

LOC105369264 (Center) rabbit polyclonal antibody, Aff - Purified

Product Data

• Application: FC, IHC, WB
• Recommended Dilution:

  Flow cytometry: 1/10-1/50.; Immunohistochemistry on Paraffin sections: 1/10-1/50.; Western blot: 1/100-1/500.; Enzyme immunoassay: 1/1000.

• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: Synthetic peptide - KLH conjugated - corresponding to the central region (between 185-215aa) of human PTPN20A.
• Specificity: This antibody recognizes PTPN20.
• Buffer: PBS with 0.09% (W/V) Sodium azide; State: Aff - Purified; State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Purified through a Protein A column followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Shipping: Blue Ice
• Database Link:
  Q4JDL3
• Background: The product of the PTPN20A (and PTPN20B) gene belongs to the family of classical tyrosine-specific protein tyrosine phosphatases. Many protein tyrosine phosphatases have been shown to regulate fundamental cellular processes and several are mutated in human diseases. Chromosome 10q contains a segmental duplication resulting in multiple copies of the protein tyrosine phosphatase, non-receptor type 20 gene. The two nearly identical copies are designated as PTPN20A and PTPN20B. A third copy is only partially duplicated and contains a pseudogene, designated as PTPN20C. This gene encodes the more telomeric copy, PTPN20B. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
• Synonyms: PTPN20A, PTPN20B, RP11-142I17.1
• Note: Molecular Weight: 26kd Isoform 6. 48423 Da

Reference Data

• Protein Families: Druggable Genome, Phosphatase