PTDSS2 (N-term) Rabbit Polyclonal Antibody

CAT#: AP53496PU-N

PTDSS2 (N-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of PTDSS2 Antibody (N-term) in MDA-MB435 cell line lysates (35ug/lane). This demonstrates the PTDSS2 antibody detected the PTDSS2 protein (arrow).

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  Formalin fixed and paraffin embedded human pancreas tissue reacted with PTDSS2 Antibody (N-term) followed by peroxidase conjugation of the secondary antibody and DAB staining.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution:

  Western Blot: 1/1000.
  Immunohistochemistry on Paraffin Sections: 1/10-1/50

• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of Human PTDSS2
• Specificity: This antibody recognizes Human PTDSS2 (N-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein A
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: phosphatidylserine synthase 2
• Database Link:
  Entrez Gene 81490 Human
  UniProt ID Q9BVG9
• Background: Phosphatidylserine (PS) accounts for 5 to 10% of cell membrane phospholipids. In addition to its role as a structural component, PS is involved in cell signaling, blood coagulation, and apoptosis. PS is synthesized by a calcium-dependent base-exchange reaction catalyzed by PS synthases (EC 2.7.8.8), like PTDSS2, that exchange L-serine for the polar head group of phosphatidylcholine (PC) or phosphatidylethanolamine (PE) (Sturbois-Balcerzak et al., 2001 [PubMed 11084049]).
• Synonyms: Phosphatidylserine synthase 2, PtdSer synthase 2, PSS-2, PSS2, Serine-exchange enzyme II
• Note: Molecular Weight: 56253 Da

Reference Data

• Protein Families: Transmembrane
• Protein Pathways: Glycerophospholipid metabolism, Metabolic pathways