PSTPIP1 (N-term) Rabbit Polyclonal Antibody

SKU AP53492PU-N

PSTPIP1 (N-term) rabbit polyclonal antibody, Aff - Purified

Product Data

• Application: WB
• Recommended Dilution:

  ELISA: 1/1000.; Western Blot: 1/100-1/500.

• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 88-118 amino acids from the N-terminal region of Human PSTPIP1 / CD28P1
• Specificity: This antibody recognizes Human PSTPIP1 / CD2BP1 (N-term).
• Buffer: PBS; State: Aff - Purified; State: Liquid purified Ig fraction; Preservative: 0.09% Sodium Azide
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein A
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Shipping: Blue Ice
• Gene Name: proline-serine-threonine phosphatase interacting protein 1
• Database Link:
  O43586
• Background: The protein encoded by this gene binds to the cytoplasmic tail of CD2, an effector of T cell activation and adhesion, negatively affecting CD2-triggered T cell activation. The encoded protein appears to be a scaffold protein and a regulator of the actin cytoskeleton. It has also been shown to bind ABL1, PTPN18, WAS, CD2AP, and PTPN12. Mutations in this gene are a cause of PAPA syndrome.
• Synonyms: PSTPIP, H-PIP, PAPAS, CD2BP1L, CD2BP1S, CD2-binding protein 1
• Note: Molecular Weight: 47591 Da

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: NOD-like receptor signaling pathway