PSTPIP1 (N-term) Rabbit Polyclonal Antibody

CAT#: AP53492PU-N

PSTPIP1 (N-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of STPIP1 / CD2BP1 Antibody (N-term) in K562 cell line lysates (35ug/lane). This demonstrates the PSTPIP1 antibody detected the PSTPIP1 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution:

  ELISA: 1/1000.
  Western Blot: 1/100-1/500.

• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 88-118 amino acids from the N-terminal region of Human PSTPIP1 / CD28P1
• Specificity: This antibody recognizes Human PSTPIP1 / CD2BP1 (N-term).
• Formulation: PBS
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.09% Sodium Azide
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein A
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: proline-serine-threonine phosphatase interacting protein 1
• Database Link:
  Entrez Gene 9051 Human
  UniProt ID O43586
• Background: The protein encoded by this gene binds to the cytoplasmic tail of CD2, an effector of T cell activation and adhesion, negatively affecting CD2-triggered T cell activation. The encoded protein appears to be a scaffold protein and a regulator of the actin cytoskeleton. It has also been shown to bind ABL1, PTPN18, WAS, CD2AP, and PTPN12. Mutations in this gene are a cause of PAPA syndrome.
• Synonyms: PSTPIP, H-PIP, PAPAS, CD2BP1L, CD2BP1S, CD2-binding protein 1
• Note: Molecular Weight: 47591 Da

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: NOD-like receptor signaling pathway