RNF70 (PJA1) (N-term) Rabbit Polyclonal Antibody

SKU AP53313PU-N

RNF70 (PJA1) (N-term) rabbit polyclonal antibody, Aff - Purified

Product Data

• Application: IHC, WB
• Recommended Dilution: ELISA: 1/1000. ; Western Blot: 1/100-1/500. ; Immunohistochemistry on Paraffin Sections: 1/10-1/50.
• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 154-183 amino acids from the N-terminal region of human PJA / RNF70
• Specificity: This antibody recognizes Human PJA1 / RNF70 (N-term).
• Buffer: PBS containing 0.09% (W/V) Sodium Azide as preservative; State: Aff - Purified; State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Shipping: Blue Ice
• Gene Name: praja ring finger ubiquitin ligase 1
• Database Link:
  Q8NG27
• Background: This gene encodes an enzyme that has E2-dependent E3 ubiquitin-protein ligase activity. This enzyme belongs to a class of ubiquitin ligases that include a RING finger motif, and it can interact with the E2 ubiquitin-conjugating enzyme UbcH5B. This gene is located in an area of chromosome X where several X-linked mental retardation disorders have been associated, and it has also been found as part of a contiguous gene deletion associated with craniofrontonasal syndrome, though a direct link to any disorder has yet to be demonstrated. Alternative splicing results in multiple transcript variants.
• Synonyms: Praja1, Praja-1, RING finger protein 70
• Note: Molecular Weight: 71002 Da

Reference Data

• Protein Families: Druggable Genome