PEX14 (Center) Rabbit Polyclonal Antibody

CAT#: AP53260PU-N

PEX14 (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of Peroxin 14 / PEX14 Antibody (Center) in mouse Neuro-2a cell line lysates (35ug/lane). This demonstrates the PEX14 antibody detected the PEX14 protein (arrow).

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  Flow cytometric analysis of Neuro-2a cells using Peroxin 14 / PEX14 Antibody (Center) (right histogram) compared to a negative control cell (left histogram). FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.

Specifications

Product Data

• Applications: FC, WB
• Recommended Dilution:

  ELISA: 1/1000.
  Western Blot: 1/100-1/500.
  Flow Cytometry: 1/10-1/50.

• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 120-150 amino acids from the Central region of Human Peroxin 14 / PEX14
• Specificity: This antibody recognizes Human and Mouse Peroxin 14 / PEX14 (Center).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: peroxisomal biogenesis factor 14
• Database Link:
  Entrez Gene 56273 MouseEntrez Gene 5195 Human
  UniProt ID O75381
• Background: This gene encodes an essential component of the peroxisomal import machinery. The protein is integrated into peroxisome membranes with its C-terminus exposed to the cytosol, and interacts with the cytosolic receptor for proteins containing a PTS1 peroxisomal targeting signal. The protein also functions as a transcriptional corepressor and interacts with a histone deacetylase. A mutation in this gene results in one form of Zellweger syndrome.
• Synonyms: Peroxin-14
• Note: Molecular Weight: 41237 Da

Reference Data

• Protein Families: Druggable Genome