PCBD1 (Center) Rabbit Polyclonal Antibody
Product Data | |
Application | FC, IHC, WB |
---|---|
Recommended Dilution | ELISA: 1/1000. Western Blot: 1/100 - 1/500. Immunohistochemistry on paraffin sections: 1/50 - 1/100. Flow Cytometry: 1/10 - 1/50. |
Reactivity | Human, Mouse |
Antibody Host | Rabbit |
Isotype | Ig |
Clonality | Polyclonal |
Immunogen | KLH conjugated synthetic peptide between 27~56 amino acids from the Center region of human PCBD1 |
Specificity | This antibody reacts to PCBD1. |
Buffer | PBS State: Aff - Purified State: Liquid purified Ig fraction Preservative: 0.09% (W/V) sodium azide |
Concentration | lot specific |
Purification | Affinity chromatography on Protein A |
Conjugation | Unconjugated |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Stability | Shelf life: one year from despatch. |
Shipping | Blue Ice |
Predicted Protein Size | 12000 Da |
Gene Name | pterin-4 alpha-carbinolamine dehydratase 1 |
Database Link | |
Background | PCBD1 encodes pterin-4 alpha-carbinolamine dehydratase, an enzyme involved in phenylalanine hydroxylation. A deficiency of this enzyme leads to hyperphenylalaninemia. The enzyme regulates the homodimerization of the transcription factor hepatocyte nuclear factor 1 (HNF1). |
Synonyms | DCOH, PCBD, PHS, Pterin carbinolamine dehydratase |
Reference Data | |
Protein Families | Druggable Genome |
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